Tråd: fettforbrenning av Grønn Te

Comment in:
Am J Clin Nutr. 2000 Nov;72(5):1232-4.

Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.

Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J.

Department of Physiology, Faculty of Medicine, University of Geneva. abdul.dulloo@unifr.ch

BACKGROUND: Current interest in the role of functional foods in weight control has focused on plant ingredients capable of interfering with the sympathoadrenal system. OBJECTIVE: We investigated whether a green tea extract, by virtue of its high content of caffeine and catechin polyphenols, could increase 24-h energy expenditure (EE) and fat oxidation in humans. DESIGN: Twenty-four-hour EE, the respiratory quotient (RQ), and the urinary excretion of nitrogen and catecholamines were measured in a respiratory chamber in 10 healthy men. On 3 separate occasions, subjects were randomly assigned among 3 treatments: green tea extract (50 mg caffeine and 90 mg epigallocatechin gallate), caffeine (50 mg), and placebo, which they ingested at breakfast, lunch, and dinner. RESULTS: Relative to placebo, treatment with the green tea extract resulted in a significant increase in 24-h EE (4%; P < 0.01) and a significant decrease in 24-h RQ [from 0.88 to 0.85; P < 0.001) without any change in urinary nitrogen. Twenty-four-hour urinary norepinephrine excretion was higher during treatment with the green tea extract than with the placebo [40%, P < 0.05). Treatment with caffeine in amounts equivalent to those found in the green tea extract had no effect on EE and RQ nor on urinary nitrogen or catecholamines. CONCLUSIONS: Green tea has thermogenic properties and promotes fat oxidation beyond that explained by its caffeine content per se. The green tea extract may play a role in the control of body composition via sympathetic activation of thermogenesis, fat oxidation, or both.

why its also good for bulking

Phytother Res. 2003 May;17(5):477-80. Related Articles, Links


Powdered green tea has antilipogenic effect on Zucker rats fed a high-fat diet.

Hasegawa N, Yamda N, Mori M.

Department of Food and Nutrition, Nagoya Bunri College, Nagoya, Japan. hsgwn@nagoya-bunri.ac.jp

The effect of powdered green tea on the lipid metabolism was studied in male Zucker rats fed a 50% sucrose diet containing 15% butter. The oral treatment of 130 mg powdered green tea per day depressed body weight increase and various adipose tissue weights but food intake was unaffected. The treatment also slightly increased the plasma triglycerides. These effects were likely mediated by the inhibition of lipogenesis in the adipose tissues. The experimental group had a higher concentration of liver total lipid, triglycerides and plasma protein, and lower liver weights than the controls. This may be due to lipid deposition in the liver because of the reduction in adipose tissue weights. It was found that powdered green tea lowered the plasma total cholesterol but liver total cholesterol was unaffected. The results indicate that the hypocholesterolemic activity of powdered green tea might be due to the inhibition of the synthesis of cholesterol in the liver. Copyright 2003 John Wiley & Sons, Ltd.

What are the fat loss benefits of EGCG?



EGCG alone and when combined with caffeine significantly increases metabolic rate[1]. Mechanism of this is likely three fold.



1. EGCG increases Cyclic amp levels[2] [3]. Increased cyclic amp means greater energy substrates available. Basically increasing energy and endurance. Studies have found that extended use of EGCG increases indurance as well as fatty acid oxidation[4].

2. EGCG inhibits breakdown of catecholamines, particularly NE( which is lipolytic) by inhibiting COMT[5] [6]. Increased levels of catecholamines means increased fatloss, increased energy levels and lowered appetite.

3. EGCG decreases food intake and suppresses appetite[7], likely due to leptin pathway activity[8] and the increases in catecholamines. Leptin is a regulator of food intake, studies indicate that EGCG has activity somewhere along the “leptin cascade”, the series of effects from leptin activity, that increases food satiety and decreases appetite.



Basically EGCG increases your ability to utilize fat for energy as well as suppressing appetite.


What are the health benefits of EGCG?



As mentioned above EGCG is a component of Green Tea which has for centuries been prized for its health benefits. Recently most of the research has focused on its benefits with respect to individual diseases. EGCG has been shown to have effect in particular on various Cancers and Diabetes.



How does EGCG fight cancer?



There is extensive evidence that EGCG is an effect chemopreventive compound. Most of the population studies have been done in Asia where green tea is widely and heavily consumed. Most of these studies indicate increased life span and less frequent occurrence of cancer, particularly prostate[9], ovarian[10] and breast[11] cancers. Studies using EGCG have shown direct impact on these cancer cell lines. EGCG exerts its activity by inhibiting mitogen-activated protein kinases, cyclin-dependent kinases, growth factor-related cell signaling, Cox-2 inhibition, activation of activator protein 1 (AP-1) and nuclear factor kappaB (NFkappaB)[12]. With respect to prostate cancer the presence of copper is essential for its greatest activity[13], this would indicate the need for supplementation with both copper and EGCG.



How does EGCG help with diabetes?



EGCG has represses hepatic glucose production and has insulin mimetic glucose clearance effects that make it a potential treatment for Type II diabetes and metabolic syndrome[14]. This means that EGCG actually acts like insulin, though it does not have the adipogenic (fat storing) effects of insulin, as well as improving insulin sensitivity. EGCG, at least in animals has been shown to protect the pancreatic islets, which means that it may protect against type 1 diabetes or at least slow the progression of this autoimmune disease[15].



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[1] Dulloo AG, Duret C, Rohrer D, et.al. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr. 1999 Dec;70(6):1040-5

[2] Dulloo AG, Seydoux J, Girardier L, et.al. Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. Int J Obes Relat Metab Disord. 2000 Feb;24(2):252-8

[3] Lorenz M, Wessler S, Follmann E, Michaelis W, et. Al., A constituent of green tea, epigallocatechin-3-gallate, activates endothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation. J Biol Chem. 2004 Feb 13;279(7):6190-5. Epub 2003 Nov 24

[4] Murase T, Haramizu S, Shimotoyodome A, Nagasawa A, Tokimitsu I. Green tea extract improves endurance capacity and increases muscle lipid oxidation in mice Am J Physiol Regul Integr Comp Physiol. 2005 Mar;288(3):R708-15. Epub 2004 Nov 24.

[5] Lu H, Meng X, Yang CS. Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate. Drug Metab Dispos. 2003 May;31(5):572-9

[6] Masuda M, Tsunoda M, Yusa Y, Yamada S, Imai K. Assay of catechol-O-methyltransferase activity in human erythrocytes using norepinephrine as a natural substrate Ann Clin Biochem. 2002 Nov;39(Pt 6):589-94

[7] Kao YH, Hiipakka RA, Liao S. Modulation of endocrine systems and food intake by green tea epigallocatechin gallate. Endocrinology. 2000 Mar;141(3):980-7

[8] Ibid.

[9] Adhami VM, Ahmad N, Mukhtar H. Molecular targets for green tea in prostate cancer prevention. J Nutr. 2003 Jul;133(7 Suppl):2417S-2424S

[10] Zhang M, Binns CW, Lee AH, Tea consumption and ovarian cancer risk: a case-control study in China. Cancer Epidemiol Biomarkers Prev. 2002 Aug;11(8):713-8

[11] Nakachi K, Suemasu K, Suga K, Takeo T, Imai K, Higashi Y. Influence of drinking green tea on breast cancer malignancy among Japanese patients. Jpn J Cancer Res. 1998 Mar;89(3):254-61.

[12] Lambert JD, Yang CS . Mechanisms of cancer prevention by tea constituents. J Nutr. 2003 Oct;133(10):3262S-3267S

[13] Yu HN, Shen SR, Xiong YK., Cytotoxicity of epigallocatechin-3-gallate to LNCaP cells in the presence of Cu(2+). J Zhejiang Univ Sci. 2005 Feb;6(2):125-31.

[14] Waltner-Law ME, Wang XL, Law BK, Hall RK, Nawano M, Granner DK . Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production. J Biol Chem. 2002 Sep 20;277(38):34933-40. Epub 2002 Jul 12

[15] Song EK, Hur H, Han MK, Epigallocatechin gallate prevents autoimmune diabetes induced by multiple low doses of streptozotocin in mice. Arch Pharm Res. 2003 Jul;26(7):559-63

Jeg har lest i endel blader at Grønn te er bra for fettforbrenning og at det motvirker
østrogen. Men jeg er litt skeptisk til dette

Bigkay

EGCG inntak på 250-500mg burde rekke et stykke men EGCG er jo ikke det eneste i GT , så man må se tilskuddet i sin helhet.

Bumper denne for en som spute om GT

Opprinnelig skrevet av McBain

Har jeg brukt sporadisk lenge!

Syntes jeg blir litt tørrere (subkutan væskereduksjon) hvis jeg tar dette ved leggetid.

Det blir du av all te siden det er generelt vanndrivende

Har du testet en grei dose Grønn te Rock , snakker nå ikke om teposer eller søppelkvalitetskapsler som ikke har annet enn antioxidant og koffein som egenskap

Ser artikkelen er over 2 år gammel nå. Er det kommet noen nyere forskning på grønn te?

PoseTE

Opprinnelig skrevet av McBain

en av studiene er jo nettopp klare på at forbrenningsøkningen til GT er langt høyere enn koffeinmengden tilsier.

En av de største misforståelsene rundt GT blant vanlieg folk er at de tror det er koffeindelen i GT som gjør noe for forbrenningen , det de ikke vet er at det er mange forskjellige TG ekstrakter og de med mest koffein i er de minst interessante.

jeg drikker grønn te ( teposer) ca. 3-4 poser om dagen. kjøpt på helsekostbutikk. mere enn det gidder jeg rett og slett ikke drikke.

effekten jeg har merket, er at jeg har fått finere hud i hvertfall. ikke så mye på forbrenning. for man best effekt av grønnte-kapsler eller holder det med teposer?

Det holder fint med teposer men du skal få drikke endel om du skal opp på samme dose EGCG som f.eks 4-5kapsler lean green

hehe, du vil at jeg skal kjøpe litt lean green av deg. men kanskje jeg gjør det. prøver litt mer på teposene og ser om jeg får behovet for mer futt

Ja gjerne ta mer enn det står på boksen , det skader nok ikke om du dobler dosen