Tråd: 'Normalt' blodtrykk er skadelig

Til blant annet Tivoli

Blood Pressure Usually Considered Normal Is Associated with an Elevated Risk of Cardiovascular Disease

Abhijit V. Kshirsagar MD, MPHa, Corresponding Author Contact Information, E-mail The Corresponding Author, Myra Carpenter PhDb, c, Heejung Bang PhDd, Sharon B. Wyatt RN, CANP, PhDe and Romulo E. Colindres MD, MSPHa

aUNC Kidney Center, School of Medicine, University of North Carolina at Chapel Hill
bDepartment of Epidemiology, University of North Carolina at Chapel Hill
cCollaborative Studies Coordinating Center, Department of Biostatistics, School of Public Health, University of North Carolina at Chapel Hill
dDivision of Biostatistics and Epidemiology, Department of Public Health, Weill Medical College, Cornell University, New York, NY
eSchools of Nursing and Medicine and Jackson Heart Study Examination Center, University of Mississippi Medical Center, Jackson

Available online 27 January 2006.


Abstract
Purpose

Research on the risk of cardiovascular disease among individuals with prehypertension (blood pressure 120/80 to 139/89 mm Hg) is incomplete. Additional information among individuals with a high risk of cardiovascular disease complications may help to focus current and future efforts.
Subjects and methods

We performed a prospective cohort analysis among 8960 middle-aged adults in the Atherosclerosis Risk in Communities (ARIC) study. The exposure variables were blood pressure levels: high normal blood pressure, systolic blood pressure 130-139 mm Hg or diastolic blood pressure 85-89 mm Hg; and normal blood pressure, systolic blood pressure 120-129 mm Hg or diastolic blood pressure 80-84 mm Hg. The outcome was incident cardiovascular disease defined as fatal/nonfatal coronary heart disease, cardiac procedure, silent myocardial infarction, or ischemic stroke. Subgroup analysis was performed among blacks, diabetics, individuals aged 55-64 years, individuals with renal insufficiency, and among individuals with varying levels of low-density lipoprotein (LDL) cholesterol and body mass index (BMI).
Results

Compared with optimal blood pressure (systolic blood pressure <120 mm Hg and diastolic blood pressure <80 mm Hg), the relative risk (RR) of cardiovascular disease for high normal blood pressure was 2.33 (95% confidence interval [CI], 1.85-2.92), and RR for normal blood pressure was 1.81 (1.47-2.22); among blacks: RR for high normal blood pressure was 3.29 (95% CI, 1.68-6.45); among diabetics: RR for high normal blood pressure 4.10 (95% CI, 2.26-7.46); age 55-64 years: RR for high normal blood pressure 2.41 (95% CI, 1.75-3.30) among individuals with renal insufficiency: RR for high normal blood pressure was 1.90 (95% CI, 1.34-2.70); among individuals with BMI >30 kg/m2: RR for high normal blood pressure was 3.56 (95% CI, 1.99-6.35); and among individuals with LDL >160 mg/dL, RR for high normal blood pressure was 1.85 (95% CI, 1.26-2.72).
Conclusions

Individuals with prehypertensive levels of blood pressure have an increased risk of developing cardiovascular disease relative to those with optimal levels. The association is pronounced among blacks, among individuals with diabetes mellitus, and among those with high BMI.

Keywords: Prehypertension; Cardiovascular disease; Cohort study

Det betyr at risikoen for kardiovaskulær sykdom er 2.3 ganger større om blodtrykket ditt er 'normalt høyt' (dvs litt forhøyet, men ikke slik at fastlegen din bryr seg nevneverdig), enn om det er normalt.

Hva om man er 15 år og har 136 i blodtrykk?

Å si at du har en fot i graven, er nok å ta litt i. Likevel kan det være lurt å foreta noen grep. Du vil neppe få utskrevet noen medisiner med et så mildt forhøyet blodtrykk, spesielt ikke siden du ikke har andre risikofaktorer (antar jeg). Derfor vil jeg anbefale å gå ned i vekt, da fortrinnsvis fett. Svi av noen kilo fett og 3-5 cm på midjen din, og jeg kan nesten garantere at mye vil forbedre seg

Ja, absolutt.